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85CuI/DMAP-Catalyzed Oxidative Alkynylation of 7-Azaindoles: Synthetic Scope and Mechanistic Studies, Vishal Talukdar, Krishanu Mondal, Devendra Kumar Dhaked, and Parthasarathi Das, Chem. Asian J. 2024, e202300987.

(Hot Article: Click Chemistry in Wiley-Vch)

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72. Recent Trends in the Synthesis and Mechanistic Implications of PhenanthridinesVishal Talukdar,  Ajesh Vijayan,  Naresh Kumar Katari,  K. V. Radhakrishnan and Parthasarathi Das, Adv. Synth. Catal. 2021, 363, 1-45

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71. Strategic Advances in Sequential C-Arylations of HeteroarenesSavio Cardoza, Manoj Kumar Shrivash, Parthasarathi Das and Vibha Tandon, J. Org. Chem., 2021, 86, 2, 1330–1356

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67. Cu(II)-catalyzed sulfonylation of 7-azaindoles using DABSO as SO2-Source and its mechanistic study Urvashi, Mohammad Ovais Dar, Prasad V. Bharatam, Parthasarathi Das, Shrikant Kukreti, Vibha Tandon, Tetrahedron, 2020, 76, 131337

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62. Programmed synthesis of triarylnitroimidazoles via sequential cross-coupling reactions, Gaurav Raina, Prakash Kannaboina, Nagaraju Mupparapu, Sushil Raina, Qazi Naveed Ahmed and Parthasarathi Das,  Org. Biomol. Chem., 2019, 17, 2134.

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61. Synthesis of 3,6-diaryl-1H-pyrazolo[3,4-b]pyridines via one-pot sequential Suzuki–Miyaura coupling, Urvashi, Vibha Tandon, Parthasarathi Das and S. Kukreti, RSC Adv., 2018, 8, 34883.

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60. Chloroform as a carbon monoxide source in palladium-catalyzed synthesis of 2-amidoimidazo[1,2-a]pyridines, P. R. Nitha, Manu M. Joseph, Greeshma Gopalan, K. K. Maiti, K. V. Radhakrishnan, Parthasarathi Das, Org. Biomol. Chem., 2018,16, 6430-6437.

52. Ruthenium-catalyzed site-selective C-H arylation of 2-pyridones and 1-isoquinolinonesK. Anil Kumar, Prakash Kannaboina, and Parthasarathi Das, Org. Biomol. Chem. 2017, 15, 5457

59. Recent Developments in the Synthesis of Pyrido[1,2-a]benzimidazoles,(Review) Rajni Khajuria, Sk. Rasheed, Chhavi Khajuria, Kamal K. Kapoor and Parthasarathi Das , Synthesis 2018, 11,  2131-2149.

56. Cobalt-Catalyzed Regioselective OrthoC(sp2)-H Bond Nitration of Aromatics through Proton-Coupled ElectronTransfer AssistanceD. Nageswar Rao, Sk. Rasheed, Gaurav Raina, Qazi Naveed Ahmed, Chaitanya Kumar Jaladanki, Prasad V. Bharatam and Parthasarathi Das, J. Org. Chem. 2017, 82, 7234.

55. Copper(II)-catalyzed Chan-Lam cross-coupling:chemoselective N-arylation of aminophenolsA. SivaReddy, K. RanjithReddy, D.Nageswar Rao, Chaitanya K. Jaladanki, Prasad V. Bharatam, Patrick Y. S. Lam and Parthasarathi Das, Org. Biomol. Chem. 2017, 15, 801(Highlights in SYNFACTS 2017).

54. β-CD/CuI catalyzed regioselective synthesis of iodo substituted 1,2,3-triazoles, imidazo[1,2-a]-pyridines and benzoimidazo[2,1-b]thiazoles in water and their functionalization, Divya Dheer, Ravindra K. Rawal, Virender Singh, P.L. Sangwan, Parthasarathi Das and Ravi Shankar , Tetrahedron 2017, 73, 4295.

53. Identification, isolation, and synthesis of seven novel impurities of anti-diabetic drug RepaglinidePrasad Kancherla, Srinivas Kessari, Pallavi Allegete, Mukkanti Khagga and Parthasarathi Das Drug Test. Analysis, 2017, 10, 212 (Highlighted in Chemistryviews).

51. Palladium-Catalyzed Chemoselective Switch: Synthesis of a New Class of Indenochromenes and Pyrano[2,3- c]carbazolesK. RanjithReddy, Prakash Kannaboina, and Parthasarathi Das, AsianJ. Org. Chem. 2017, 6, 534 (Hot Article in Wiley-Vch).

49. Nickel-Catalyzed C(Aryl)-O Bond Activation/Cross-Coupling Reaction of Carbazoles with Methyl Grignard: Synthesis of Ellipticine, D. Nageswar Rao, Sk. Rasheed, and Parthasarathi Das, AsianJ. Org. Chem. 2016, 5, 1499 (Hot Article in Wiley-Vch).

48. Cobalt(II)-Catalyzed C-N Bond Formation: Synthesis of Aryl- Substituted Imidazo[1,2-a]pyridinesD. Nageswar Rao, Sk. Rasheed, and Parthasarathi Das, AsianJ. Org. Chem. 2016, 5, 1213(Most read article).

47. Copper-Catalyzed CNH2 Arylation of 2-Aminobenzimidazoles and Related C-Amino-NH-azolesD. Nageswar Rao, Sk. Rasheed, K. Anil Kumar, A. Siva Reddy, and Parthasarathi Das, Adv. Synth. Catal. 2016, 358, 2126.

46. Nickel-Catalyzed Chan-Lam cross-coupling: Chemoselective N-arylation of 2-aminobenzimidazoleK. Anil Kumar, Prakash Kannaboina, D.Nageswar Rao and Parthasarathi Das, Org. Biomol. Chem. 2016, 14, 8989.

45. Metal-Free Aminooxygenation of Alkynes: Efficient Synthesis of 3-Aroylimidazo[1,2-a]-N-HeterocyclesK. Ranjith Reddy, Ajai Prakash Gupta and Parthasarathi Das, AsianJ. Org. Chem. 2016, 5, 900.

44. Cu(I)-catalyzed double C–H amination: synthesis of 2-iodo-imidazo[1,2-a]pyridines†Divya Dheer, K. Ranjith Reddy, Santosh K. Rath, P. L. Sangwan, Parthasarthi Das and Ravi Shankar, RSC Adv., 2016,6, 38033.

43. Copper-Catalyzed N-Arylation of Tautomerizable Heterocycles with Boronic Acids and Its Application to Synthesis of Oxygenated Carbazoles,

 K. Anil Kumar, Prakash Kannaboina, Devendra K. Dhaked, Prasad V. Bharatam, and Parthasarathi Das, Chemistry Select, 2016, 1, 601.

42. Site-selective Intermolecular Oxidative C-3 Alkenylation of 7-Azaindoles at Room TemperaturePrakash Kannaboina, K. Anil Kumar and Parthasarathi Das, Org. Lett. 2016, 18, 900 (Most read article).

41. Copper-Catalyzed Inter- and Intramolecular C−N Bond Formation: Synthesis of Benzimidazole-Fused Heterocycles, Sk. Rasheed, D. Nageswar Rao, and Parthasarathi Das, J. Org. Chem. 2015, 80, 9321 (Most read article).

40. Palladium-catalyzed arylation of 2H-chromene: A new entry to pyrano[2,3-c]carbazoles, K. Ranjith Reddy, A. Siva Reddy, Devendra K. Dhaked, S. K. Rasheed, Anup Singh Pathania, Ravi Shankar, Fayaz Malik, and Parthasarathi Das, Org. Biomol. Chem. 2015, 13, 9285.

39. Copper-Catalyzed Oxidative C-H Amination: Synthesis of Imidazo[1,2-a]-N-Heterocycles from NHeteroaryl Enanminones, K. Ranjith Reddy, A. Siva Reddy, Ravi Shankar, Rajni kant and Parthasarathi Das, AsianJ. Org. Chem. 2015, 4, 573 (Hot Article in Wiley-Vch).

38. Cu-catalyzed arylation of the amino group in the indazole ring: regioselective synthesis of pyrazolocarbazoles, K. Anil Kumar, Prakash Kannaboina, Devendra K. Dhaked, Ram A. Vishwakarma, Prasad V. Bharatam,
and Parthasarathi Das, Org. Biomol. Chem. 2015, 13, 1481.

37. Divergent synthesis of 4, 6-diarylated pyridin-2(1H)-ones from chalcones: novel access to 2,4,6-triaryl pyridines, Rajni Khajuria, Prakash Kannaboina, Kamal K. Kapoor, Annah Gupta, Gaurav Raina, Amanpreet Kaur Jassal, Love Karan Rana, Maninder S. Hundal and Parthasarathi Das, Org. Biomol. Chem. 2015, 13, 5944.

36. Sulphuric acid immobilized on silica gel (H2SO4– SiO2) as an eco-friendly catalyst for transamidation, Sk. Rasheed, D. Nageswar Rao, A. Siva Reddy, Ravi Shankar and Parthasarathi Das, RSC Adv. 2015, 5, 10567.

35. Copper- catalyzed sequential N-arylation of C-amino-NH-azoles, D. Nageswar Rao, Sk. Rasheed, Ram A. Vishwakarma and Parthasarathi Das, Chem. Commun. 2014, 50, 12911.

34. Hypervalent iodine(III) catalyzed oxidative C–N bond formation in water: synthesis of benzimidazole-fused heterocycles, D. Nageswar Rao, Sk. Rasheed, Ram A. Viswakarma and Parthasarathi Das, RSC Adv. 2014, 3, 25600.

33. C-N bond formation via Cu-catalyzed cross coupling with boronic acids leading to methyl carbazole-3-carboxylate: Synthesis of carbazole alkaloids,

 Sk. Rasheed, D. Nageswar Rao, K. Ranjith Reddy, S. Aravanda, Ram A. Vishwakarma and Parthasarathi Das, RSC Adv. 2014, 4, 4960.

32. Direct C-2 Arylation of 7-Azaindoles: Chemoselective Access to Multiarylated Derivatives, K. Prakash, K. AnilKumar, S. Aravinda, Ram A. Vishwakarma and Parthasarathi Das, Org. Lett. 2013, 15, 5718.

31. Base and ligand-free copper-catalysed N-arylation of 2-amino-N-heterocycles with boronic acids in airD. Nageswar Rao, Sk. Rasheed, S. Aravinda, Ram A. Viswakarma, Parthasarathi Das, RSC Adv. 2013, 3, 11472.

30. Synthesis and characterisation of 5-(6-substituted Phenyl-2H-Chromen-3yl)oxazole derivativesP. Sadanandam, V. Jyothi, M. Adharvanachari, Parthasarathi Das, K. Mukkanti, Letters in Organic Chemistry. 2012, 9, 863.

29. Synthesis and characterization of 9-methyl-2-morpholin-4-yl-8-substituted phenyl-1H-purine derivatives using polyphosphoric acid(PPA) as an efficient catalystP. Sadanandam, V. Jyothi, M. Adharvanachari, Parthasarathi Das, K. Mukkanti Tetrahedron Lett. 2011,52,5521

28. Direct Synthesis of N-aryl derivatives of quinazolin-4(3H)-ones employing arylboronic acids in the presence of Cu(OAc)2K. Sreeramamurthy, Ettam Ashok, Velisoju Mahendar, G. Santoshkumar and Parthasarathi Das, Synlett 2010, 721.

27. Dithiocarbamate and DBU promoted amide bond formation under microwave conditionK. Nareshkumar, K. Sreeramamurthy, Sadananda Palle, Khagga Mukkanti and Parthasarathi Das, Tetrahedron Lett. 2010, 51, 899 (Highlighted in www. organic-chemsitry.org).

26. An efficient synthesis of VareniclineSrinivas Pasikanti, D. Srinivas Reddy, B. Venkatesham, P. K. Dubey, Javed Iqbal and Parthasarathi Das, Tetrahedron Lett. 2010, 51, 151.

 


25. Total Synthesis of (±)-Petasitolone and (±)-FukinoneSrinivas Pasikanti, D. Srinivas Reddy, Javed Iqbal, P. K. Dubey and Parthasarathi Das, Synthesis 2009, 3833.

 


24. Studies toward the total synthesis of rhizoxin D: Stereoselective preparation of the C11-C19 fragmentSrinivas Padakanti, Chetlur Kirankumar, Ettam Ashok and Parthasarathi Das, Synthesis, 2009, 2709.

 


23. Stereoselective Preparation of C1-C10 and C11-O14 Fragments of Narbonolide: Exploiting the Versatility of Thiazolidinethione Chiral AuxiliaryC. Prasad Narasimhulu and Parthasarathi Das, Synthesis 2009, 957.

 


22. A Cross Metathesis Approach to the Synthesis of key Precursor of the Macrolide Core of Rhizoxin DSrinivas Padakanti, Bukkapattanam R.Sreekanth, Velisoju Mahendar, Manojit Pal, Khagga Mukkanti, Javed Iqbal and Parthasarathi Das, Synlett 2008, 2417.

 


21. A new route to eremophilanes: synthesis of (±)-eremophilenolide, (±)-eremophiledinone, and (±)- deoxyeremo petasidione, P. Srinivas, D. Srinivasa Reddy, K. Shiva Kumar, P. K. Dubey, Javed Iqbal and Parthasarathi Das, Tetrahedron Lett. 2008, 49, 6084.

 


20. Studies toward the total synthesis of narbonolide: Stereoselective preparation of the C1-C10 fragmentC. Prasad Narasimhulu, Javed Iqbal, Khagga Mukkanti and Parthasarathi Das, Tetrahedron Lett. 2008, 49, 3185.

 


19. A Stereoselective Synthesis of Macrolide Core of MigrastatinParthasarathi Das, Vobbalareddy Saibaba, Chetlur Kirankumar, Velisoju Mahendar, Synthesis, 2008, 445.

 


18. Dithiocarbamate and CuO promoted one-pot synthesis of 2-(N-substituted)-aminobenzimidazoles and related heterocyclesParthasarathi Das, C. Kirankumar, K. Nareshkumar, Md. Innus, Javed Iqbal, Nanduri Srinivas, Tetrahedron Lett. 2008, 49, 992.

 


17. Studies Toward the Total Synthesis of (-)-Dictyostatin: Stereoselective Preparation of the C1-C10 FragmentVobbalareddy Saibaba, Alwar Sampath, Khagga Mukkanti, Javed Iqbal and Parthasarathi Das, Synthesis 2007, 2797.

 


16. Synthesis and Biological Evaluation of C-2, C-8 and N-9 trisubstituted Purines as Aurora-A kinase Inhibitors, Parthasarathi Das, C. Kirankumar, Srinivas Nanduri, Shanavas Alikunju, Rahul Banerjee and Javed Iqbal, Med.Chem. Res. 2007, 15, 79.

 

 


15. A cross metathesis approach to the synthesis of the C11-C23 fragment of (-)-16-normethyldictyostatinV. Sai Baba, Parthasarathi Das, K. Mukkanti and Javed Iqbal, Tetrahedron Lett. 2006, 47, 7927.

 


14. A convergent synthesis of macrolide core of migrastatinV. Sai Baba, Parthasarathi Das, K. Mukkanti and Javed Iqbal, Tetrahedron Lett. 2006, 47, 6083.

                                                                                                       Postdoctoral Research


13. Direct Observation of ESR Spectra of Bicyclic Nine-membered Endiynes at ambient Temperature, Masahiro Hirama, Kimoio Akiyama, Parthasarathi Das, Takashi Mita, Martin J. Lear, Kyo-ichiro Iida, Itaru Sato, Fumihiko Yoshimura, Toyonobu Usuki and Shozo Tero-Kuboto Heterocycles 2006, 69, 83.

 


12. Spin-Trapping of 13C-Labeled p-Benzynes, Generated via the Masamune-Bergman Cyclisation of Bicyclic Nine-Membered EnediynesToyonobu Usuki, Takashi Mita, Martin J. Lear, Parthasarathi Das, Fumihiko Yoshimra, Masayuki Inoue, Masahiro Hirama, KimioAkiyama and Shozo Tero-Kuboto, Angew.Chem. Int. Ed. 2004, 39, 5249.

 


11. Asymmetric Synthesis of Cycloalkenyl and Alkenyloxiranes from Allylic Sulfoximines and Aldehydes and application to Solid-Phase SyntheisHans-Joachim Gais, Gadamsetti S. Babu, Markus Gunter and Parthasarathi Das, Eur. J.Org. Chem. 2004, 1464.

 

10. Asymmetric synthesis of protected -substituted and -disubstituted -amino acids bearing branched hydroxyalkyl side chains and of protected 1, 3-amino alcohols with three contiguous stereogenic centers from allylic sulfoximines and aldehydesHans-Joachim Gais, Ralf Loo, Daniel Roder, Parthasarathi Das and Gerhard Rabbe, Eur. J. Org. Chem. 2003, 1500.

 


9. Synthesis of 13C-labelled , bicyclic mimetics of natural enediynesParthasarathi Das, Takashi Mita, Martin J. Lear and Masahiro Hirama, Chem. Commun. 2002, 2624.

 


8. Diastereoselective additions of ethynyl Grignard reagent to erythrulose derivativesShoji Kobayashi, Parthasarathi Das, Guang Xing Wang, Takashi Mita, Martin J. Lear and Masahiro Hirama, Chem. Lett. 2002, 300.

 


7. Diastereoselective amination of vinylic sulfoximines: Application to the asymmetric synthesis of functionalised -substituted and -disubstituted -amino acids and of -amino alcohols, Hans-Joachim Gais, Ralf Loo, Parthasarathi Das and Gerhard Rabbe, Tetrahedron Lett. 2000, 41, 2851.

 


6. N-Methylsulfonimidoyl substituted (2-alkenyl) titanium complexes: Application to the Synthesis of - and -sulfonimidoyl substituted chiral homoallylic alcohols, X-ray crystal structure analysis and fluxional behaviorHans-Joachim Gais, Rüdiger Hainz, Harald Müller, Peter Richard Burns, Nicole Giesen, Gerhard Rabbe, Jan Runsink, Sabine Nienstedt, Jürgen Decker, Marcel Schleusner, Jochen Hachtel, Ralf Loo, Chang-wan Woo and Parthasarathi Das, Eur. J. Org. Chem. 2000, 3973.

                                                                                     Doctoral Research

 


5. Photoinduced Electron Transfer (PET) promoted oxidative activation of N-benzyl-N-methylglycyl-(S)-prolinol: Development of novel strategies towards enantioselective synthesis of -amino acids, their N-methyl derivatives and -hydroxy acids employing (S)-prolinol as a recyclable chiral auxiliaryGanesh Pandey, Parthasarathi Das and P. Yella Reddy, Eur. J. Org. Chem. 2000, 657.

 


4. Synthesis and utilisation of chiral 3-hydroxy perhydropyrrolo[2,1-c][1,4]oxazin-4-one as a novel precursor for the enantioselective synthesis of -hydroxy carboxylic acidsGanesh Pandey, Parthasarathi Das and P.Yella Reddy, Tetrahedron Lett. 1998, 39, 7153.

 


3. Synthesis and utilisation of chiral 3-N-benzyl-N-methylaminoperhydropyrrolo[2,1-c][1,4]oxazin-4-one as novel precursor for the enantioselective synthesis of -aminoacids and their N-methyl derivativesGanesh Pandey and Parthasarathi Das, J. Indian.Chem. Soc. 1998, 634.

 


2. Enantioselective -alkylation of piperidine via chiral perhydropyrido[2,1-b][1,3,4]-oxadiazinone : An easy route for the synthesis of both enantiomers of coniineGanesh Pandey and Parthasarathi Das, Tetrahedron Lett. 1997, 38, 9073.

 


1. Synthesis and utilisation of a novel glycine derived chiral precursor, based on a recyclable L-Prolinol auxiliary for the enanatioselective preparation of -amino acids and their N-methyl derivativesGanesh Pandey, P.Yella Reddy and Parthasarathi Das, Tetrahedron Lett. 1996, 37, 3175.

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